PBIO-538 Syllabus

Week

Topic & Lecturer

1

Introduction/Origins of Central Hormones

 

Determinants of sex and gender
Ali Hassan, PhD, Assistant Professor of Medicine
Overview of the major hormonal axes
Ali Hassan, PhD, Assistant Professor of Medicine

2

Hypothalamus and Pituitary Hormones and Actions

 

The hypothalamic-pituitary-adrenal axis and the adrenal gland
Darren Roesch, PhD, Assistant Professor of Medicine
Additional anterior pituitary hormones- prolactin, growth hormone, thyroid hormone- sex differences
Jacqueline Jonklaas, MD, PhD, MPH, Assistant Professor of Medicine

3

The Posterior Pituitary and the Renin-Angiotensin-Aldosterone Axis

 

The posterior pituitary- vasopressin and oxytocin
Eric Glasgow, PhD, Assistant Professor of Medicine
The renin-angiotensin-aldosterone axis
Eric Glasgow, PhD, Assistant Professor of Medicine

4

Blood Pressure and the Cardiovascular Pathology

 

Hormonal determinants of blood pressure regulation
Christine Maric, PhD, FAHA, FASN, Assistant Professor of Medicine
Cardiovascular-renal disease and pathologies
Christine Maric, PhD, FAHA, FASN, Assistant Professor of Medicine

5

Pancreatic Hormones and Energy Metabolism

 

Insulin and glucagons
Carolyn A. Ecelbarger, PhD, Assistant Professor of Medicine
The metabolic syndrome, insulin resistance, and obesity
Carolyn A. Ecelbarger, PhD, Assistant Professor of Medicine

6

Hormonal Control of Food Intake

 

Hormonal control of food intake- central and peripheral signaling
Darren Roesch, PhD, Assistant Professor of Medicine
Novel therapies for obesity- gender differences
Darren Roesch, PhD, Assistant Professor of Medicine

7 Mid-Term
 

Mid-term Review
Mid-term Exam

8

No class- Spring Break

9

Vitamin D/calcitonin/PTH

 

Mineral and electrolyte metabolism- Ca, P, K, Na
Julianna Barsony, MD, PhD, Professor of Medicine)
Skeletal disorders/amenorrhea/and growth disorders
Julianna Barsony, MD, PhD, Professor of Medicine

10

Body composition and respiration

 

Muscle growth, body composition, and sex steroids
Christine Maric, PhD, FAHA, FASN, Assistant Professor of Medicine
Respiration and exercise physiology
Christine Maric, PhD, FAHA, FASN, Assistant Professor of Medicine

11

Gastrointestinal function and aging

 

GI function and hormonal signaling
Carolyn A. Ecelbarger, PhD, Assistant Professor of Medicine
Aging and hormone replacement
Carolyn A. Ecelbarger, PhD, Assistant Professor of Medicine

12

The brain, cognition, and mood

 

Mood disorders and depression
Eric Glasgow, PhD, Assistant Professor of Medicine
Hormones and higher cognitive functioning
Eric Glasgow, PhD, Assistant Professor of Medicine

13

Role of hormones in normal maturation and aging

 

Hormones along the lifespan and gender differences
Ana Paula Dantas, PhD, Assistant Professor of Medicine
No class Easter Break

14

Reproduction and sexual functioning

 

Reproduction and parturition
Ana Paula Dantas, PhD, Assistant Professor of Medicine
Sexual dysfunction and infertility
Ana Paula Dantas, PhD, Assistant Professor of Medicine

15

Drug metabolism and cancer

 

Sex differences in common drug metabolism
Julianna Barsony, MD, PhD, Professor of Medicine
Role of sex and sex steroids in cancer
Julianna Barsony, MD, PhD, Professor of Medicine

16 Paper
 

Papers Due
No class, independent study

17

Final Exam

 

Grade Distribution
10% Participation/Class Attendance
30% Midterm Examination
30% Final Examination
30% Research Paper